ArterioVenous Malformation of the brain

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Arteriovenous malformations (AVMs) are  type of vascular malformation most relevant to the surgical pathologist. Because  their vessels tend to leak and induce gliosis.  AVMs can present with seizure disorder and also cause spontaneous hemorrhage. Best seen by trichrome or elastic stains, AVMs manifest artery-vein connections with associated arterialization of veins. Arterialization is thickening of a venous wall to the point where it resembles an artery, possibly due to fibrotic reaction to shunted arterial blood. Arteries show irregular duplication or loss of elastin . Thrombi are common. (Sternberg’s 5th ed)

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